Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2201251 | Neurochemistry International | 2011 | 10 Pages |
Abstract
- MSCs are known to form mesenchymal derivatives but may also have a neurogenic function.
- Evidence shows MSCs engrafted into the nervous system survive, migrate and positively effect recovery from neural deficits.
- Three mechanisms by which MSCs may restore neural function have been proposed, with MSC-derived paracrine factors most likely to induce endogenous repair.
- MSCs are potential candidates for use in therapies to treat neurological disorders.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cell Biology
Authors
Daniel J. Maltman, Steven A. Hardy, Stefan A. Przyborski,