| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2202433 | Results in Immunology | 2012 | 5 Pages |
Abstract
Histone H2A participates in host defense responses by producing antimicrobial peptides (AMPs). The present study deals with identification of a putative antimicrobial sequence, Himanturin from the histone H2A of Round Whip Ray, Himantura pastinacoides. A 204 bp fragment encoding 68 amino acid residues was amplified from cDNA of Round Whip Ray, H. pastinacoides. Himanturin exhibited high similarity to previously reported histone H2A derived AMPs indicating the presence of an antimicrobial sequence motif. Physicochemical properties of Himanturin suggest it to be a potential antimicrobial candidate.
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Authors
Naveen Sathyan, Rosamma Philip, E.R. Chaithanya, P.R. Anil Kumar, Swapna P. Antony,