Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2203141 | Seminars in Cell & Developmental Biology | 2009 | 7 Pages |
Abstract
The human brain exhibits notable asymmetries. Little is known about these symmetry deviations; however scientists are beginning to understand them by employing the lateralized zebrafish epithalamus as a model. The zebrafish epithalamus consists of the pineal and parapineal organs and paired habenular nuclei located bilateral to the pineal complex. While zebrafish pineal and parapineal organs arise from a common population of cells, parapineal cells undergo a separate program that allows them to migrate left of the pineal anlage. Studying the processes that lead to brain laterality in zebrafish will allow a better understanding of how human brain laterality is established.
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Authors
Corey D. Snelson, Joshua T. Gamse,