| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2203207 | Seminars in Cell & Developmental Biology | 2008 | 8 Pages |
Abstract
Chlamydomonas reinhardtii has two apically localized flagella that are maintained at an equal and appropriate length. Assembly and maintenance of flagella requires a microtubule-based transport system known as intraflagellar transport (IFT). During IFT, proteins destined for incorporation into or removal from a flagellum are carried along doublet microtubules via IFT particles. Regulation of IFT activity therefore is pivotal in determining the length of a flagellum. Reviewed is our current understanding of the role of IFT and signal transduction pathways in the regulation of flagellar length.
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Authors
Nedra F. Wilson, Janaki Kannan Iyer, Julie A. Buchheim, William Meek,