Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2203304 | Seminars in Cell & Developmental Biology | 2008 | 11 Pages |
Abstract
Lens-containing eyes are a feature of surprisingly broad spectrum of organisms across the animal kingdom that represent a significant improvement of simple eye composed of just photoreceptor cells and pigment cells. It is apparent that such an upgrade of animal visual system has originated numerous times during evolution since many distinct strategies to enhance light refraction through the use of lens and cornea have been utilized. In addition to having an ancient role in prototypical eye formation Pax transcription factors were convergently recruited for regulation of structurally diverse crystallins and genes affecting morphogenesis of various lens-containing eyes.
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Authors
Kristyna Jonasova, Zbynek Kozmik,