Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2204835 | Trends in Cell Biology | 2010 | 4 Pages |
Abstract
The next revolution in microscopy is upon us: it is High-Throughput Imaging (HTI). In HTI large numbers of images from many samples are acquired and analyzed. This has become possible due to a confluence of dramatic progress in microscope engineering, enabling efficient image collection, and the availability of high computing power for data analysis. Combining HTI with genome-wide RNA interference (RNAi)-based gene knockdown technology offers a powerful approach for unbiased discovery of cellular mechanisms.
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Authors
Vassilis Roukos, Tom Misteli, Christine K. Schmidt,