Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2204853 | Trends in Cell Biology | 2010 | 12 Pages |
Abstract
Armadillo (ARM)-repeat proteins form a large family with diverse and fundamental functions in many eukaryotes. ARM-repeat proteins have largely been characterised in multicellular organisms and much is known about how a subset of these proteins function. The structure of ARM-repeats allows proteins containing them to be functionally very versatile. Are the ARM-repeat proteins in ‘little creatures’ as multifunctional as their better-studied relatives? The time is now right to start analysing ARM-repeat proteins in these new systems to better understand their cell biology. Here, we review recent advances in understanding the many cellular roles of both well-known and novel ARM-repeat proteins.
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Authors
Rita Tewari, Elizabeth Bailes, Karen A. Bunting, Juliet C. Coates,