Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2205140 | Trends in Cell Biology | 2008 | 4 Pages |
Abstract
Some epithelia contain cells with multiple motile cilia that beat in a concerted manner. New tools and experimental systems have facilitated molecular studies of cilium biogenesis and the coordinated planar polarization of cilia that leads to their concerted motility. A recent elegant study using embryonic frog epidermis demonstrates that Dishevelled, a key regulator of both the Wnt–β-catenin and planar cell polarity pathways, controls both the docking and planar polarization of ciliary basal bodies.
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Authors
Eszter K. Vladar, Jeffrey D. Axelrod,