Article ID Journal Published Year Pages File Type
2205140 Trends in Cell Biology 2008 4 Pages PDF
Abstract

Some epithelia contain cells with multiple motile cilia that beat in a concerted manner. New tools and experimental systems have facilitated molecular studies of cilium biogenesis and the coordinated planar polarization of cilia that leads to their concerted motility. A recent elegant study using embryonic frog epidermis demonstrates that Dishevelled, a key regulator of both the Wnt–β-catenin and planar cell polarity pathways, controls both the docking and planar polarization of ciliary basal bodies.

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