Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
228289 | Journal of Industrial and Engineering Chemistry | 2012 | 5 Pages |
Abstract
We fabricated a disposable DNA hybridization sensor using pentacene thin film transistors (TFTs) on flexible substrate. The analytes, 100-mer ss-DNA (poly A and poly T) or 100 bp ds-DNA were immobilized directly on the surface of the pentacene layer, thereby producing a dramatic change in the electrical properties of the devices. The electrical characteristics of devices were studied as a function of DNA immobilization conditions, DNA concentrations and between ss- and ds-DNA. Based on these results, we propose a disposable label-free sensor for DNA hybridization through direct measurement of electrical properties by the immobilization of DNA on flexible pentacene TFTs.
Keywords
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Physical Sciences and Engineering
Chemical Engineering
Chemical Engineering (General)
Authors
Jung-Min Kim, Sandeep Kumar Jha, Dong-Hoon Lee, Rohit Chand, Jun-Ho Jeun, Yong-Sang Kim,