Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
228660 | Journal of Industrial and Engineering Chemistry | 2009 | 6 Pages |
Abstract
Solution phase synthetic method for amyloid-cleaving catalysts was developed, which bears triazine core, scaffold with bulky and that have various solubility properties; Co(III) complex of cyclen (1,4,7,10-tetraazacyclododecane) for catalytic group, and two imaging agents for binding group. This synthetic method was identified by H-NMR, C-NMR for intermediates and MS for the last products. The yields by this method surpassed solid phase synthesis and took much lower labor, expense, and time. The products which were synthesized by solution phase synthetic method showed good catalytic activities.
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Physical Sciences and Engineering
Chemical Engineering
Chemical Engineering (General)
Authors
Keunhong Jeong, Min Kyum Kim, Woo Young Chung, Young Sik Kye, Ji-Hyun Kim, Junghun Suh,