Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
229436 | Journal of Saudi Chemical Society | 2016 | 7 Pages |
Abstract
A variety of 3,5-diphenyl-6-(5-p-toly1-[1,3,4] thiadiazol-2yl)-3,3a,5,6 tetrahydro-2H pyrazolo[3,4-d]thiazole 6ag were synthesized by the reaction of chalcone derivatives of [1,3,4] thiadiazol-2-yl)-thiazolidin-4-one 5a–g with hydrazine hydrate. The chemical structures of these compounds were confirmed by IR, NMR (1H & 13C) and mass spectral studies. Synthesized compounds 6a–g were evaluated for their antimicrobial and anti-tubercular activities. Some of the compounds exhibited well antimicrobial and anti-tubercular activities compared to the standard drugs.
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Authors
Nareshvarma Seelam, S.P. Shrivastava,