Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
229590 | Journal of Saudi Chemical Society | 2011 | 7 Pages |
Abstract
A new series of 6-iodo-2-thienylquinazolin-4(3H)-one and its fused heterocyclic analogs were prepared and screened for their antimicrobial activity. Compounds 4, 8, 14 and 24 showed remarkable broad spectrum antimicrobial activity. The fused heterocycles, 1,2,4-triazino[3,4-c]quinazoline, benzimidazo[1,2-c]quinazoline and quinazoline-bearing thiazolidinone moiety proved to contribute for antimicrobial activity. The detailed synthesis and their antimicrobial screening are reported.
Keywords
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Physical Sciences and Engineering
Chemical Engineering
Chemical Engineering (General)
Authors
Ahmed M. Alafeefy, Adel S. El-Azab, Menshawy A. Mohamed, Mohamed Afroz Bakhat, S.G. Abdel-Hamid,