Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
229916 | Journal of Saudi Chemical Society | 2009 | 4 Pages |
Abstract
QSAR studies on a series of inhibitors for anti-apoptotic Bcl-2 proteins based on BHI-1 were performed the activities are found to correlate well with some topological parameters and steric parameters. The results are critically discussed on the basis of regression data, Pogliani factor Q and cross validation technique. The results are found to be useful in discussing the mechanism of drug–receptor interaction.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Chemical Engineering (General)
Authors
A.K. Srivastava, Akanchha Srivastava, Archana, Meetu Jaiswal, Arpita Nath,