Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
232078 | The Journal of Supercritical Fluids | 2007 | 8 Pages |
Biologically active lignans from caulomas (stems) and leaves of Schisandra chinensis were extracted with supercritical carbon dioxide at the pressures 20–27 MPa, temperatures 40, 50 and 60 °C, and solvent-to-feed ratio 36–43. Six major lignans were determined by means of HPLC: schizandrin, gomisin A, deoxyschizandrin, γ-schizandrin, gomisin N and wuweizisu C. At the optimum conditions 27 MPa and 50 °C, the extraction yield of lignans from caulomas was 1.3% dry weight and their content in the extract was higher than 32 wt.%. At the optimum conditions for CO2 extraction from S. chinensis leaves, 27 MPa and 60 °C, the yield of lignans was 0.22% d.w. and the yield of (E)-cinnamic acid was 0.18% d.w. Addition of 2–4% ethanol to CO2 increased the extraction rate but not the final yield of lignans. The solubility of extracted substances in supercritical CO2 was estimated from their extraction rates.