Article ID Journal Published Year Pages File Type
2402777 Vaccine 2012 7 Pages PDF
Abstract
► HA substitutions in influenza pandemic H1N1 vaccine were analysed. ► Specific substitutions affecting increased antigen yield identified. ► A specific novel glycosylation site is associated with increased yield. ► Substitutions affecting yield were not transferrable between vaccine viruses.
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Related Topics
Life Sciences Immunology and Microbiology Immunology
Preview
An additional oligosaccharide moiety in the HA of a pandemic influenza H1N1 candidate vaccine virus confers increased antigen yield in eggs
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