Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2403932 | Vaccine | 2010 | 8 Pages |
Abstract
We estimate the impact of the two previous influenza seasonal vaccines and the pandemic vaccine on risk of A (H1N1) 2009 laboratory confirmed hospitalizations during the autumn 2009 pandemic wave in Castellón, Spain. We conducted a test-negative, hospital-based, case–control study. Influenza A (H1N1) 2009 infection was detected in 147 (44%) of 334 patients hospitalized for a presumptive influenza related illness. No effect was observed for the 2008–2009 and 2009–2010 seasonal influenza vaccines. However, the pandemic vaccine was associated with an adjusted vaccine effectiveness of 90% (95% CI, 48–100%). Pandemic vaccines were effective in preventing pandemic influenza associated hospitalizations.
Keywords
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Immunology and Microbiology
Immunology
Authors
Joan Puig-Barberà, Alberto Arnedo-Pena, Francisco Pardo-Serrano, María Dolores Tirado-Balaguer, Silvia Pérez-Vilar, Ester Silvestre-Silvestre, Consuelo Calvo-Mas, Lourdes Safont-Adsuara, Montserrat Ruiz-García,