Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2405786 | Vaccine | 2009 | 4 Pages |
Abstract
Several case reports have described immune hemolytic anemia (IHA) following vaccination in children. We examined the risk of IHA in the 42 days following vaccination exposure using a self-controlled case series study design. In our population-based cohort of nearly 4.5 million children in the Vaccine Safety Datalink, we identified 55 confirmed cases of new-onset IHA from 1991 through 2000. We found no association between IHA and diphtheria–pertussis–tetanus vaccination (incidence rate ratio (IRR) = 0.65, 95% CI: 0.19–2.24), hepatitis B vaccination (IRR = 1.73, 95% CI: 0.59–5.01), or any vaccination (IRR = 1.04, 95% CI: 0.46–2.32).
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Authors
Allison L. Naleway, Edward A. Belongia, James G. Donahue, Burney A. Kieke, Jason M. Glanz,