Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2407057 | Vaccine | 2009 | 5 Pages |
Abstract
The possible interference of tamoxifen with anti-tumor vaccines was studied in a translational view of combined preventive approaches. Tamoxifen treatment of HER-2/neu transgenic mice combined to anti-HER-2/neu cell vaccine did not hamper the efficacy of cancer immunoprevention, and caused a significantly increased production of interferon-γ. These data suggest that tamoxifen could even have a positive impact on the efficacy of cancer immunoprevention.
Keywords
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Immunology
Authors
Carla De Giovanni, Giordano Nicoletti, Lorena Landuzzi, Stefania Croci, Arianna Palladini, Agnese Antognoli, Annalisa Murgo, Marianna L. Ianzano, Valentina Grosso, Valeria Stivani, Manuela Iezzi, Piero Musiani, Patrizia Nanni, Pier-Luigi Lollini,