Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2407411 | Vaccine | 2008 | 4 Pages |
Abstract
As part of safety monitoring during a group B meningococcal disease vaccination campaign in New Zealand, we examined the possible excess risk of vaccine-associated simple febrile seizures (SFS). We conducted a cohort analysis using data from active hospital-based surveillance in the South Auckland area and a national immunisation register. Based on analysis of approximately 63,000 doses, we found no statistically significant increase in SFS incidence within 1, 2, 4, or 7 days after vaccination for any/all doses administered to children aged 6 months through 4 years. We concluded that the vaccine is unlikely to induce a heightened risk of SFS.
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Immunology and Microbiology
Immunology
Authors
Paul Stehr-Green, Sarah Radke, Charlotte Kieft, Yvonne Galloway, Anne McNicholas, Stewart Reid,