Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2407691 | Vaccine | 2008 | 8 Pages |
Abstract
The limited production capacity for vaccines raises the question what the best strategy is for allocating the vaccine to mitigate an influenza pandemic. We developed an age-structured model for spread of an influenza pandemic and validated it against observations from the Asian flu pandemic. Two strategies were evaluated: vaccination can be implemented at the start of the influenza pandemic, or vaccination will be implemented near the peak of it. Our results suggest prioritizing individuals with a high-risk of complications if a vaccine becomes available during a pandemic. If available at the start, vaccinating school children might be considered since this results in slightly lower expected number of deaths.
Keywords
Related Topics
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Immunology and Microbiology
Immunology
Authors
Sido D. Mylius, Thomas J. Hagenaars, Anna K. Lugnér, Jacco Wallinga,