| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2407735 | Vaccine | 2008 | 5 Pages |
Abstract
The influenza viruses are characterized by segmented, negative-strand RNA genomes requiring an RNA-dependent RNA polymerase of viral origin for replication. The particular structure of the influenza virus genome and function of its viral proteins enable antigenic drift and antigenic shift. These processes result in viruses able to evade the long-term adaptive immune responses in many hosts.
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Authors
Nicole M. Bouvier, Peter Palese,