Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2408898 | Vaccine | 2007 | 6 Pages |
Abstract
Yellow fever vaccine-associated viscerotropic disease (YEL-AVD) is a rare complication of yellow fever (YF) vaccination. A previously healthy 22-year-old female died following YF vaccination despite aggressive measures. Serial viral load titers, cytokine levels and host genetic factors were evaluated in an attempt to understand this unusual and lethal outcome. The patient's high-titer vaccine viremia and possibly related minor genetic anomalies provide clues to exploring the etiology of YEL-AVD.
Keywords
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Immunology
Authors
Jon L. Belsher, Peter Gay, Margo Brinton, Joseph DellaValla, Robert Ridenour, Robert Lanciotti, Andrey Perelygin, Sherif Zaki, Christopher Paddock, Troy Querec, Tuofu Zhu, Bali Pulendran, Rachel B. Eidex, Edward Hayes,