Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2409777 | Vaccine | 2006 | 5 Pages |
To evaluate the Brighton Collaboration case definition of acute intussusception, we reviewed all episodes reported to the Swiss Paediatric Surveillance Unit (SPSU) during 1 year (4/2003–3/2004). Of 96 confirmed episodes 86 (90%, 95% CI 83–96) were captured by the case definition. Of the remaining 10 episodes, 9 resolved spontaneously following presentation with clinical signs and symptoms, and ultrasound findings compatible with intussusception. Eighty-two episodes met level 1 of the definition, the highest level of diagnostic certainty. Compared to level 1, the sensitivity of level 2 (intermediate level) and level 3 (lowest level) was 65% (CI 55–74) and 30% (CI 20–40), respectively. In conclusion, the case definition was useful and applicable to assess the background rate of intussusception in the light of potential future rotavirus immunization.