| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2430285 | Developmental & Comparative Immunology | 2007 | 5 Pages |
Abstract
Melanization is regulated by the prophenoloxidase cascade and functions as a response to intruding microorganisms in invertebrates. When injecting dsRNA of the lepidopteran immune protein hemolin in pupae of Hyalophora cecropia (Lepidoptera: Saturniidae), we observed a significant reduction in phenoloxidase activity after 24 h, but not after 72 h. The link between hemolin and the prophenoloxidase system suggests that hemolin is a pattern recognition protein important for the triggering of the prophenoloxidase cascade in the defence against bacterial infections.
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Authors
Olle Terenius, Raul Bettencourt, So Young Lee, Wenli Li, Kenneth Söderhäll, Ingrid Faye,