| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2473345 | Current Opinion in Virology | 2014 | 6 Pages |
•High throughput protocols (‘-omics’) have uncovered mechanisms of herpesvirus pathogenesis.•Although increasingly common, ‘-omics’ assessment of roseoloviruses has yet to be performed.•Reagents exist to study HHV-6A but resources need to be developed to study HHV-6B and HHV-7.
Recent technological advances have led to an explosion in the system-wide profiling of biological processes in the study of herpesvirus biology, herein referred to as ‘-omics’. In many cases these approaches have revealed novel virus-induced changes to host cell biology that can be targeted with new antiviral therapeutics. Despite these successes, -omics approaches are not widely applied in the study of roseoloviruses. Here we describe examples of how -omics studies have shaped our understanding of herpesvirus biology, and discuss how these approaches might be used to identify host and viral factors that mediate roseolovirus pathogenesis.
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