Giant viruses in the environment: their origins and evolution

The recent identification of giant viruses has raised important questions, not only regarding their origin and evolution, but also regarding the differentiation between viruses and living organisms. These viruses possess large genomes encoding genes potentially involved in various metabolic processes and even protein synthesis, indicating their putative autonomy. Giant viruses of the Phycodnaviridae and Mimiviridae families appear to share a common evolutionary ancestor with members of the nucleo-cytoplasmic large DNA viruses. Many giant viruses are associated with protists in aquatic environments and might have evolved in protist cells. They may therefore play important roles in material cycling in natural ecosystems. With the advent of environmental metagenomic projects, there will be more chances to encounter novel giant viruses in the future.

► Many giant viruses are associated with protists in aquatic environments. ► Giant viruses appear to share a common evolutionary ancestor with NCLDVs. ► Giant viruses have more protein-encoding genes than many bacteria. ► Giant viruses may play important roles in material cycling in natural ecosystems.