| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2490463 | Medical Hypotheses | 2011 | 4 Pages |
Abstract
Recent evidence suggests that covalent modifications to the genomic platform in the brain, that is DNA and its surrounding histones, provide a stable potentially lifelong mechanism for remembrance. Consequently, the making and unmaking of memories is accessible through pharmacological manipulations of these modifications. This has implications for psychotherapy and long-term rehabilitation of CNS disorders. We hypothesize that by enhancing learning through pharmacologically manipulating ‘epigenetic’ parameters, the effects of psychotherapies and rehabilitation can be enhanced.
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Authors
David P. Gavin, Kayla A. Chase, Rajiv P. Sharma,