Article ID Journal Published Year Pages File Type
2495582 Pharmaceutical Methods 2013 5 Pages PDF
Abstract
The present study describes degradation of reserpine under different ICH prescribed stress conditions (acid and base hydrolysis, oxidation, dry and wet heat degradation and photo-degradation) and establishment of stability indicating HPTLC assay. The drug undergoes degradation under acidic and basic conditions, oxidation, dry and wet heat treatment and photo degraded. As the method could effectively separate the drug form its degradation products, it can be employed as a stability indicating one.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Molecular Medicine
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