| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2497098 | Phytomedicine | 2010 | 4 Pages |
Abstract
Betulinic acid (1), isolated from the crude extract of the leaves of Pentalinon andrieuxii (Apocynaceae), together with betulinic acid acetate (2), betulonic acid (3), betulinic acid methyl ester (4), and betulin (5) were evaluated for their antiprotozoal activity. The results showed that modifying the C-3 position increases leishmanicidal activity while modification of the C-3 and C-28 positions decreases trypanocidal activity.
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Authors
D.B. Domínguez-Carmona, F. Escalante-Erosa, K. García-Sosa, G. Ruiz-Pinell, D. Gutierrez-Yapu, M.J. Chan-Bacab, A. Giménez-Turba, L.M. Peña-Rodríguez,