| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2497862 | Phytomedicine | 2009 | 6 Pages |
Abstract
Acetone extract of Elephantopus scaber, an ethnomedicnal plant, reduced the blood glucose levels in streptozotocin-induced diabetic rats significantly. Acute toxicity studies revealed the non-toxic nature of the crude extract. Fractionation of the acetone extract yielded a new steroid, 28Nor-22(R)Witha 2,6,23-trienolide. Biological testing of the compound demonstrated a significant antidiabetic activity by reducing the elevated blood glucose levels and restoring the insulin levels in streptozotocin-induced diabetic rats. This compound can be a useful candidate to treat diabetes.
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Authors
P. Daisy, R. Jasmine, S. Ignacimuthu, E. Murugan,