Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2498099 | Phytomedicine | 2007 | 12 Pages |
Abstract
Inhibition of acetylcholinesterase (AChE), the key enzyme in the breakdown of acetylcholine, is considered as a promising strategy for the treatment of neurological disorders such as Alzheimer's disease, senile dementia, ataxia and myasthenia gravis. A potential source of AChE inhibitors is certainly provided by the abundance of plants in nature. This article aims to provide a comprehensive literature survey of plants that have been tested for AChE inhibitory activity. Numerous phytoconstituents and promising plant species as AChE inhibitors are being reported in this communication.
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Authors
Pulok K. Mukherjee, Venkatesan Kumar, Mainak Mal, Peter J. Houghton,