| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2510238 | Antiviral Research | 2011 | 4 Pages |
Abstract
⺠We study antiviral effect of tenofovir on CaMV in Brassica pekinensis grown in vitro. ⺠Tenofovir (25-50 mg/l) reduced CaMV concentration in plants within 6-9 weeks. ⺠Virus-free plants were obtained after 3-month cultivation on medium with tenofovir. ⺠We proved metabolism of tenofovir in B. pekinensis leaves but not in roots. ⺠Mono- and diphosphate analogs of NDP and/or NTP are the only metabolites formed.
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Authors
Josef Å pak, Ivan Votruba, Daniela Pavingerová, AntonÃn Holý, Vlastimila Å paková, Karel Petrzik,