| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2510834 | Antiviral Research | 2010 | 8 Pages |
Abstract
Diammonium glycyrrhizin (DG), a salt from glycyrrhizinate (GL) that is a major active component of licorice root extract with various pharmacological activities was investigated for its inhibitory effect on pseudorabies virus (PrV) infection. In parallel, lithium chloride (LiCl), a chemical reagent with potential antiviral activity was compared with DG for their inhibitory ability against PrV infection in vitro. Virus plaque-reduction assays, PCR and RT-PCR analysis indicated that both drugs inhibited cell infection by PrV. Moreover, addition of the drugs resulted in fewer apoptotic cells during PrV infection.
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Authors
Xiuwen Sui, Jiechao Yin, Xiaofeng Ren,