Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2511557 | Antiviral Research | 2006 | 6 Pages |
Abstract
The discovery that some nucleoside analogues endowed with the unnatural l-configuration can possess biological activities has been a significant breakthrough in antiviral chemotherapy. In this regard, lamivudine (3TC) was the first l-nucleoside enantiomer approved against HIV and HBV, and several other l-nucleosides are currently under clinical development as antiviral agents
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Authors
Christophe Mathé, Gilles Gosselin,