| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2525092 | Biomedicine & Pharmacotherapy | 2013 | 4 Pages |
Abstract
The expression profiling analysis of inflammatory chemokines and their receptors in newly formed lymph nodes in breast cancer was carried out. The analysis revealed the increase in expression of the genes CCL16, XCR1, CYFIP2, TNFSF14 and the reduction in expression of chemokine ligands CXCL5 and CXCL12 in tertiary lymphoid organs. The obtained results allow us to suggest that the process of induction of lymph nodes neogenesis is identical (in its key mechanisms) to the process of lymphoid tissue neogenesis in autoimmune diseases and in some infections, but may have different triggers.
Keywords
Related Topics
Health Sciences
Medicine and Dentistry
Oncology
Authors
S.K. Gantsev, K. Umezawa, D.V. Islamgulov, E.K. Khusnutdinova, R.S. Ishmuratova, V.Y. Frolova, S.R. Kzyrgalin,