A new monoterpenoid indole alkaloid from Ervatamia chinensis

AimTo study the chemical constituents of the whole plants of E. chinensis, and find new or effective components.MethodsCompounds were isolated by repeated silica gel and Sephadex LH-20 column chromatography. The structures were elucidated by NMR and HRESI-MS spectrometry.ResultsSix alkaloids were isolated from whole plants of E. chinensis, and their structures were elucidated as ervachinine E (1), rutaecarpine (2), 1–methyl–2–nonyl–4(1H)–quinolone (3), dihydroevocarpine (4), evocarpine (5), and 1–methyl–2–[(Z)–6–undecenyl]–4(1H)-quinolone (6), respectively.ConclusionCompound 1 is a new monoterpenoid indole alkaloid and with moderate anti-tumor activity, while compounds 2–6 are reported from this species for the first time.