A new 1, 10-secoguaianolide from the aerial parts of Artemisia anomala

AimTo study chemical constituents of the aerial parts of Artemisia anomala (Asteraceae).MethodsThe constituents were isolated with silica gel, ODS column chromatography and semi-preparative HPLC, and their structures were elucidated on the basis of physical characteristics and spectral data.ResultsEight compounds were obtained, and their structures were identified as 3β-ethoxytanapartholide (1), (4S*, 5S*)-dihydro-5-[(1R*, 2S*)-2-hydroxy-2-methyl-5-oxo-3-cyclopenten-1-yl]-3-methylene-4-(3-oxobutyl)- 2(3H)-furanone (2), ligucyperonol (3), cyperusol C (4), santamarin (5), 1a, 2a, 3a, 4a, 10a -pentahydroxyguaia-11(13)-ene-12, 6a-olide (6), balanophonin (7), methyl 3-(2'-hydroxy-4'-methoxyphenyl) propanoate (8).ConclusionCompound 1 was a new artifact, 4 and 8 were isolated from the genus Artemisia for the first time, and compounds 2–3, 5–7 were isolated from this plant for the first time.