Propinic Lactones A and B, Two New Triterpenoids from Schisandra propinqua var. propinqua and the Significance in Biosythesis Pathway

AimTo study the chemical constituents of the aerial parts of Schisandra propinqua var. propinqua.MethodSilica gel, C18 reversed phase silica gel and HPLC were used. The structures were elucidated by extensive spectroscopic methods.ResultTwo new triterpenoids, propinic lactone A (1) with 3, 4-seco-cycloartane skeleton, and propinic lactone B (2) possessing 3, 4:9, 10-seco-cycloartane skeleton, together with a known typical cycloartane triterpenoid, schizandronic acid (3), have been isolated and identified.ConclusionThese two new triterpenoids serve as two important bridge intermediates from cycloartane triterpenoids to Schisandra nortriterpenoids biogenetically.