Chemical Constituents of Toona ciliata var. pubescens

AimTo study the chemical constituents of the leaves and stems of Toona ciliata var. pubescens.MethodSilica gel column chromatography, Sephadex LH-20 gel column chromatography and preparative HPLC were employed for the isolation and purfication. The structures were identified on the basis of spectroscopic data and chemical evidence.Results23 Compounds were isolated from the 95% ethanol extract of the leaves and stems of T. ciliata var. pubescens, and their structures were identified as siderin (1), 4, 6, 7-trimethoxy-5-methylcoumarin (2), isoscopoletin (3), scopoletin (4), 6, 7-dimethoxycoumarin (5), 7-hydroxy-6, 8-dime-thoxycoumarin (6), dehydrodiconiferyl alcohol (7), (−)-lariciresinol (8), thero-2, 3-bis-(4-hydroxy-3-methoxypheyl)-3-methoxy-propanol (9), cycloeucalenol (10), 8(14), 15-isopimaradiene-2, 3, 19-triol (11), 3S, 5R-dihydroxy-6R, 7-megstigmadien-9-one (12), (−)-loliolide (13), (+)-catechin (14), dimethyl malate (15), diisobutyl phthalate (16), dibutyl phthalate (17), 1, 3, 5-trimethoxybenzene (18), syringic acid (19), syringaldehyde (20), vanillic acid (21), vanillin (22), and 3, 3′, 5, 5′-tetra-tert-butyl-2, 2′-dihydroxybiphenyl (23).ConclusionAll compounds were isolated from this plant for the first time.