Chemical constituents from the roots of Polyalthia obliqua

AimTo study the chemical constituents from the roots of Polyalthia obliqua.MethodsThe constituents were isolated and purified by silica gel column chromatography, Sephadex LH-20 and preparative TLC. Their structures were identified on the basis of spectral data and physiochemical properties.ResultsTen compounds were isolated and their structures were elucidated as 5,7-dihydroxy-8-formyl-6-methylflavanone (1), demethoxymatteucin ol (2), 5,7-dihydroxy-6-methyl-8-formylflavone (3), 5, 7-dihydroxy-6-formyl-8-methylflavone (4), marcanine A (5), suberosol (6), β-sitosteral (7), vanillin (8), cinnamic acid (9) and nicotinic acid (10).ConclusionCompounds 1-4 were reported from the genus for the first time. All the compounds were isolated from this plant for the first time. Compound 6 showed cytotoxicity against human cancer cell lines SPC-A-1 and SGC-7901.