Three cerebrosides from the sea cucumber Cucumaria frondosa

AimTo study the chemical constituents of the sea cucumber Cucumaria frondosa.MethodsThree sphingosine-type glucocerebrosides, CF-3-1, CF-3-2 and CF-3-3 were isolated by means of high performance liquid chromatography (HPLC) from a cerebroside molecular species 3 which was obtained from the less polar fraction of the 65% EtOH extract of the sea cucumber Cucumaria frondosa Gunnerus.ResultsThe structures of these cerebrosides were determined on the basis of chemical and spectroscopic evidences.ConclusionThree compounds were isolated from the sea cucumber Cucumaria frondosa for the first time. CF-3-3 and CF-3-2 were obtained as pure compounds for the first time.