Optical coherence tomography: basics, current application and future potential

Optical coherence tomography is a relatively novel imaging modality that utilizes light to generate high resolution images of intravascular structures. As result, OCT has rapidly become a preferred modality for imaging intracoronary structures such as coronary plaques and coronary stents. OCT is increasingly being utilized to further our understanding of intracoronary pathology and the effects of therapies both pharmacologic and procedural on the coronary vasculature. This review is intended to give an overview of the current investigational uses of OCT and its potential roles as the technology matures.

Graphical abstractFigure optionsDownload full-size imageDownload high-quality image (202 K)Download as PowerPoint slideHighlights► Optical coherence tomography (OCT) provides high resolution images of intravascular structures. ► OCT can provided unique insights into coronary pathology. ► High resolution OCT images can guide coronary intervention and evaluate the vascular response to intravascular stents. ► OCT has significant potential as a tool in evaluating drugs targeting coronary artery disease. ► Further studies are needed to establish a role for OCT in guiding clinical decision making.