Article ID Journal Published Year Pages File Type
2530210 Current Opinion in Pharmacology 2010 6 Pages PDF
Abstract

We survey the current paradigm for cancer therapy and offer a perspective on the state of clinical oncology. Next, we address the key clinical and biological obstacles that have hampered progress to date. Recent insights into the true genetic complexity of cancer, the mixed clinical performance of targeted therapies, and the homogeneity of industry pipelines argue for new approaches to cancer therapy.

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Authors
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