Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2531791 | European Journal of Pharmacology | 2014 | 4 Pages |
Abstract
Opioids are among the most frequently used analgesics for treatment of severe pain. However, certain of their side-effects, particularly ventilatory disturbances, often restrict their use. Separation of analgesia from respiratory depression has long been a goal in the basic research and therapeutic use of opioids. This report briefly describes opioid-induced respiratory depression and possible pharmacological strategies to counteract this without affecting analgesia.
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Authors
Satoko Kimura, Akira Haji,