Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2532523 | European Journal of Pharmacology | 2011 | 11 Pages |
Abstract
Autism spectrum disorders (ASDs) are pervasive neurodevelopmental disorders, characterized by impairments in social interaction and communication and the presence of limited, repetitive and stereotyped interests and behavior. Bowel symptoms are frequently reported in children with ASD and a potential role for gastrointestinal disturbances in ASD has been suggested. This review focuses on the importance of (allergic) gastrointestinal problems in ASD. We provide an overview of the possible gut-to-brain pathways and discuss opportunities for pharmaceutical and/or nutritional approaches for therapy.
Keywords
Related Topics
Life Sciences
Neuroscience
Cellular and Molecular Neuroscience
Authors
Caroline G.M. de Theije, Jiangbo Wu, Sofia Lopes da Silva, Patrick J. Kamphuis, Johan Garssen, S. Mechiel Korte, Aletta D. Kraneveld,