Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2541094 | International Immunopharmacology | 2011 | 4 Pages |
Abstract
Sinomenine (SN), a pure compound extracted from the Sinomenium acutum plant, has been found to inhibit T- and B-lymphocyte activation, proliferation and function and to interfere with the differentiation, recruitment and function of several other cell types, such as dendritic cells (DC). SN has demonstrated its potential anti-inflammatory role for treating immune-related disorders in experimental animal models and in some clinical applications. This review will summarize its potential effects, mechanisms and applications.
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Authors
Quanxing Wang, Xiao-Kang Li,