Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2541379 | International Immunopharmacology | 2010 | 5 Pages |
Abstract
Recent studies in animal models have demonstrated that adoptive transfer of antigen-specific CD4+CD25+ regulatory T cells (Tregs) can prevent or even cure autoimmune diseases, and appear to induce transplantation tolerance. Thus, adoptive cell therapy using ex vivo induced and expanded patient-specific CD4+CD25+Tregs has emerged as a promising individualized medicine for the treatment of inflammatory disease. Here we discuss our current efforts on the pursuit of regulatory T cell therapy for the induction of transplantation tolerance.
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Authors
Shuiping Jiang, Julia Tsang, Paul Tam,