| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2542480 | International Immunopharmacology | 2007 | 5 Pages |
Abstract
Synthesized N-(1-deoxy-β-d-fructopyranos-1-yl)-l-proline (Fru-Pro), an Amadori rearrangement product, has been investigated for its immunomodulatory effects. We evaluated the effects of Fru-Pro on the in vivo and in vitro activity in the regulation of the mice immune response. Haemagglutination antibody titre, plaque forming cell assay, E-rosette forming assay and cytotoxic test were studied. It has been demonstrated that the compound shows immunostimulating properties. In conclusion, present investigation suggests that the Fru-Pro is biologically functional, improves the immune system and might be regarded as an immune response modulator.
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Authors
Mirosław Tarnawski, Renata Kuliś-Orzechowska, Bogdan Szelepin,