Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2552361 | Life Sciences | 2010 | 7 Pages |
Abstract
These findings suggest that nicotinamide has a protective effect against PARP-1-induced astrocyte death and that its transporter-mediated uptake, which is extracellular pH-sensitive and common to N-methylnicotinamide, is critical for prevention of PARP-1-triggered cell death.
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Authors
Eri Suzuki, Hiroto Okuda, Kentaro Nishida, Sadaki Fujimoto, Kazuki Nagasawa,