| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2552660 | Life Sciences | 2010 | 7 Pages |
Abstract
The increased Ad5RSVβgal-mediated transgene expression in the VK2 cells is due to the increased RSV promoter activity in VK2 cells. Our results point out that (i) drug-resistance may be accompanied with an alteration in promoter activity; (ii) the proper choice of promoter could contribute to a decrease in the vector dose required to achieve a therapeutic effect during gene therapy.
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Authors
Dragomira Majhen, Anamaria Brozovic, Tvrtko Buger, Jelka Gabrilovac, Maja Osmak, Andreja AmbrioviÄ-Ristov,